articlesandhow.com articlesandhow.com
Main About Us Security & Privacy ToS Add Url Submit Article
Search:   
 

Common Denominator - Quickly and Easily!

We can get the LCD by decomposing each bottom into primes. This method is general, but slow and trou ... - Victor Guskov
 

An Examination of Non-Hodgkins Lymphoma

Cancer is a life-threatening disease that is prevalent in our time. One of which is known as non-Hod ... - Morgan Hamilton
 

Whiting New Jersey Feeds Water to Aliens on Mars; Read All About It!

A recent Immigrant to New Jersey starts a Nudist Colony in 1944 after launching a Successful Spring ... - Christopher Jon Luke Dowgin
 
 

SBIR 1996 Human Genome Awards Announced

In July the DOE Office of Health and Environmental Research announced awards in human genome topics ... - Aaron Hall
 

How To Auto Security System For Your Car

How to find the best Auto Security System , to protect family and yourself, even if you know nothing ... - Jintonic Sos
 

Genome Project Finishes Fifth Year Ahead of Schedule

October 1 marked the fifth anniversary of the Human Genome Project in the United States. This issue ... - Aaron Hall
 

Abatement; Comprehensive and Non-Linear Strategies Needed

When considering abatement strategies to remove bio-toxins, bio contaminants, insects, noxious weeds ... - Lance Winslow
 

How Volcanoes Affect Our Climate

Scientists believe that large volcanic eruptions can have an effect on global climate, the gas and d ... - Michael Russell
 
 

  Main » Education & Learning » Science Courses
   
 

Early History of Small Genome Sequencing

   
In 1977, bacteriophage phi-x174 (5386bp) became the first organism to be sequenced completely, by Sanger and colleagues [Nature 246, 687 (1977)]. In 1982, bacteriophage lambda (48,502bp) was completed using a strategy based on sequencing random fragments of DNA, in this case produced by digesting the lambda genome with restriction enzymes, again by Sanger and colleagues [J. Mol. Biol. 162, 729 (1982)].

Thirteen years elapsed before the first nonviral organism was sequenced completely, this time using whole-genome random sequencing and assembly, called shotgun sequencing. In July1995, Fleischmann and colleagues reported the completion of Haemophilus influenzae (1,830,137bp), the first free-living organism to be sequenced [Science 269, 469 (1995)]. At the end of 1995, the complete DNA sequence of Mycoplasma genitalium (580,070bp), another free-living organism, was published by Fraser and colleagues. M. genitalium DNA encoded only 470 predicted ORFs, providing an estimate for the minimal number of genes needed to support life [Science 270, 349 (1995)].

Since 1995, complete genomic sequences have been published or made available for four more organisms: Methanococcus jannaschii, an Archaeon; Synechosystis, a cyanobacterium species; Mycoplasma pneumoniae, a eubacterium closely related to M. genitalium; and the yeast Saccharomyces cerevisiae, the first eukaryotic organism to be completely sequenced.

Author: Aaron Hall
 
Author Bio:

 
 
 

Related Articles

 
Is Dish TV a Valuable Alternative
 
Kids in School? Check Out the School Systems Before You Buy a New Home
 
Genome Researchers Seek Cancer Gene
 
Bogus Distance Learning Degrees - How Can You Tell?
 
Teaching - A Survival Guide for Students and New Teachers (Part 4) Body language basics
 
Everything You Ever Wanted To Know About Ozone
 
Las Vegas Schools Open New Schools and Hire New Teachers
 
Learning Chinese: Mission Impossible
 
1999 Hollaender Winners Announced*
 
Increasing Applications of Micro Bubbles
 
 
 
Get Multiple Links
 
   

Issues & News

   

Computers & Networking

   

Sports & Adventure

   

Self Help

   

Education & Learning

   

Society & Communities

   

Games & Play

   

Culture & Art

   

Fitness & Health

   

Jobs & Employment

   

Property & Agents

   

Garden & Home

   

Shopping Online

   

Science & Space

   

Finance & Banking

   

Relationship & Lifestyle

   

Business & Commerce

   

Law & Politics

   

Teens & Children

   

Healthcare & Treatment

   

Recreation & Entertainment

   

Travel & Vacation

   

Food & Recipe

   

Vehicles & Automotive

 
Main >> Security & Privacy >> ToS
Copyright © 2008 www.articlesandhow.com